HCID 20643060, compound → HCID 18362932, compound

HRID 369473Notes

Reaction equation

HRID 369473 reaction equation
OCCC#CC1N(CC2C3C(=CC=CC=3)C=CC=2)C=C2C=1CN(C)CN2CC(C)C.[OH:31][CH2:32][CH2:33][C:34]#[C:35][C:36]1[N:37]([CH2:52][C:53]2[C:62]3[C:57](=[CH:58][CH:59]=[CH:60][CH:61]=3)[CH:56]=[CH:55][CH:54]=2)[CH:38]=[C:39]2[C:44]=1[C:43](=[O:45])[N:42]([CH3:46])[C:41](=[O:47])[N:40]2[CH2:48][CH:49]([CH3:51])[CH3:50]>>[OH:31][CH2:32][CH2:33][CH2:34][CH2:35][C:36]1[N:37]([CH2:52][C:53]2[C:62]3[C:57](=[CH:58][CH:59]=[CH:60][CH:61]=3)[CH:56]=[CH:55][CH:54]=2)[CH:38]=[C:39]2[C:44]=1[C:43](=[O:45])[N:42]([CH3:46])[C:41](=[O:47])[N:40]2[CH2:48][CH:49]([CH3:51])[CH3:50]

Participants

3

Reactant 2

HCID 20643060HCID 20643060, compoundHCID 86755959HCID 86755959, compound

Product 1

HCID 18362932HCID 18362932, compound

Procedure

The title compound was prepared from the compound of Example 15, 5-(4-hydroxybut-1-ynyl)-3-methyl-1-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo [3,4-d]pyrimidine-2,4(3 H,6 H)-dione, in a manner analogous to the method of Example 14 above.

Sources & evidence

ORD record
ord-e2efbbbbd715499ab4c420cbb7898fb9
Source dataset
uspto-grants-2000_10
Patent number
US06136974

Reaction notes

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