HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Acridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Isatin | HCID 7054 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | Acridine | HCID 9215 | — |
Reaction Steps
The isatin product was refluxed in 110 mL of 10% KOH solution in water over night. The dark green mixture was cooled and acidified with 400 mL of 1:1 ice/5M HCl. The solid was washed with water and air-dried yielding the acridine acid. 1H NMR (DMSO-d6) δ 7.81-7.94 (m, 4H), 8.31-8.36 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06139782 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-5c84b6e6fadf4bc3a55ced04ab90b4ed |
| Source note | uspto-grants-2000_10 |