HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → Methyl-4-(trans-2-decenyloxy)-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 2-Decen-1-ol | HCID 87630 | — |
| Reactant | Methyl 4-(octadecyloxy)benzoate | HCID 4189536 | — |
| Reactant | Diethyl azodicarboxylate | HCID 5462977 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Methyl-4-(trans-2-decenyloxy)-benzoate | HCID 18521070 | 65% |
Reaction Steps
Phenol 34 (486 mg, 3.2 mmol), 2-decenol 26 g (500 mg, 3.2 mmol), TPP (965 mg, 3.68 mmol), and DEAD (641 mg, 3.68 mmol) in 32 ml ether were reacted according to the procedure for compound 35a. The crude product was purified via flash chromatography over silica gel with gradual elutions from 95/5-90/10 (v/v, Hex/EtOAc). Evaporation of solvent yielded 603 mg (65%) of colorless needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06139771 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-18a140bcba8640bf90b50ad97f4e25ab |
| Source note | uspto-grants-2000_10 |