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HRID369541

反应详情

EQUATION

反应方程式

HRID 369541 的结构方程式

REACTANTS

反应物

3
结构：CCCCCCCCCCCCCCCCCCOc1ccc(C(=O)OC)cc1
HCID4189536

Methyl-4-octadecyloxy-benzoate

C26H44O3

结构：CCOC(=O)/N=N/C(=O)OCC
HCID5462977

(E)-Diethyl azodicarboxylate

C6H10N2O4

结构：COC(=O)c1ccc(-c2ccc(O)c([N+](=O)[O-])c2)cc1
HCID18521036

Methyl 4'-hydroxy-3'-nitro[1,1'-biphenyl]-4-carboxylate

C14H11NO5

PRODUCTS

生成物

1
结构：CCCCCCCC[C@H](C)Oc1ccc(-c2ccc(C(=O)OC)cc2)cc1[N+](=O)[O-]
HCID54059652

未命名化合物

收率 66%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

DEAD (323 mg, 1.85 mmol), phenol 40 (440 mg, 1.61 mmol), R-2-decanol (268 mg, 1.69 mmol), and TPP (486 mg, 1.85 mmol) in 16 ml anhydrous ether were reacted according to the procedure for compound 35a. The crude product was concentrated and purified via flash chromatography over silica gel with gradual elutions from 95/5 to 65/35 (Hex/EtOAc). Evaporation of the solvent yielded 439 mg (66%) of a yellow solid.

WORKUP

后处理

  1. concentrationThe crude product was concentrated
  2. custompurified via flash chromatography over silica gel with gradual elutions from 95/5 to 65/35 (Hex/EtOAc)
  3. customEvaporation of the solvent