Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triphenylphosphine → 3-Ethyl-5-methyl-1-benzoyloxy-4-(4-(3-methyl-2-butenyloxy)butyloxy)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | Diisopropyl diazene-1,2-dicarboxylate | HCID 75555 | — |
| 반응물 | 4-[(3-Methylbut-2-en-1-yl)oxy]butan-1-ol | HCID 23282389 | — |
| 반응물 | 2-Ethyl-6-methyl-4-benzoyloxyphenol | HCID 23282409 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-Ethyl-5-methyl-1-benzoyloxy-4-(4-(3-methyl-2-butenyloxy)butyloxy)benzene | HCID 23282410 | 79% |
반응 단계
To a mixture of 0.52 g of 4-(3-methyl-2-butenyloxy)butanol, 0.77 g of 2-ethyl-6-methyl-4-benzoyloxyphenol, 0.87 g of triphenylphosphine and 20 ml of tetrahydrofuran was slowly added dropwise 0.73 g of diisopropyl azodicarboxylate with stirring under ice cooling. After stirring at room temperature for 6 hours, the reaction mixture was concentrated. The residue was subjected to silica gel chromatography, which afforded 0.94 g of 3-ethyl-5-methyl-1-benzoyloxy-4-(4-(3-methyl-2-butenyloxy)butyloxy)benzene (yield, 79%), nD20.0 1.5361.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06140274 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-9d5aacd313c64550bdb3121819980b13 |
| 출처 메모 | uspto-grants-2000_10 |