6-Chloro-2,3-dihydro-1h-indole → 4-(6-Chloro-2,3-dihydroindol-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine

HRID 369712Notes

Reaction equation

HRID 369712 reaction equation
Cl[C:2]1[C:3]2[CH:10]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=3)[NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[Cl:20][C:21]1[CH:29]=[C:28]2[C:24]([CH2:25][CH2:26][NH:27]2)=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:29]=[C:28]2[C:24]([CH2:25][CH2:26][N:27]2[C:2]2[C:3]3[CH:10]=[C:9]([C:11]4[CH:16]=[CH:15][C:14]([N+:17]([O-:19])=[O:18])=[CH:13][CH:12]=4)[NH:8][C:4]=3[N:5]=[CH:6][N:7]=2)=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 2585676-Chloro-2,3-dihydro-1h-indoleHCID 212626054-Chloro-6-(4-nitrophenyl)-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 232824594-(6-Chloro-2,3-dihydroindol-1-yl)-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]-pyrimidine

Procedure

This product is prepared in a manner analogous to that described in Example 6 from 4-chloro-6-(4-nitro-phenyl)-7H-pyrrolo[2,3-d]pyrimidine and 6-chloro-2,3-dihydroindole (1.1 equivalents).

Workup

  1. customThis product is prepared in a manner analogous to

Sources & evidence

ORD record
ord-2088f27e579143d19626dc88da29d5ef
Source dataset
uspto-grants-2000_10
Patent number
US06140317

Reaction notes

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