HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 369775Generated: October 30, 2026
Sodium Bicarbonate → HCID 135708790, compound
https://huagongshe.com/reaction/369775
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Ethyl 4-Amino-2-fluorobenzoate | HCID 10797532 | — |
| Reactant | 9-bromomethyl-3-methylbenzo[f]quinazolin-1(2H)-one | HCID 135400976 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 135708790 | HCID 135708790 | — |
Reaction Steps
To a 500 mL 3-neck flask equipped with a magnetic stirrer, a nitrogen inlet, and a reflux condenser were added 5.00 g of 9-bromomethyl-3-methylbenzo(f)quinazolin-1(2H)-one, 3.02 g of ethyl 4-amino-2-fluorobenzoate, 4.17 g of NaHCO3, and 42 mL of anhydrous DMF. The reaction mixture was heated to 100° C. with stirring under nitrogen for 1.5 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06140100 |
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| Source dataset | uspto-grants-2000_10 |
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| ORD ID | ord-7cc06ed0ea3f467da69ef7a398ba103c |
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| Source note | uspto-grants-2000_10 |
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