Cyclohexene → HCID 18968462, compound

Participants

Reaction Steps

According to example 61, 10.0 g of 2-iodobenzyl alcohol was treated with 25 mL of cyclohexene (Aldrich) using 0.96 g of Pd(O Ac)2, 2.60 g of tri-ortho-tolyphosphine, and 6.6 mL of Et3N at 100° C. for 48 h. The resulting olefin mixture was hydrogenated for 6.5 h using 0.36 g of 5% Pt(C) in MeOH to afford 3.37 g (42%) of 2-cyclohexyl benzyl alcohol as a light yellow liquid.

Provenance & Evidence