HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20706043, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isobutylene | HCID 8255 | — |
| Reactant | HCID 20706030 | HCID 20706030 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 20706043 | HCID 20706043 | 87% |
Reaction Steps
According to example 54, 0.50 g of 3-tert-butyl-L-phenylalanine·HCl was treated with 30 mL of isobutylene in 25 mL of 1,4-dioxane in the presence of 0.4 mL of conc. H2SO4. Work-up in the usual manner followed by acidification of the free amine with ethereal HCl afforded 0.53 g (87%) of tert-butyl 3-tert-butyl-L-phenylalaninate·HCl as a light yellow foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06140100 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-925a4d2623e441468491e364d2eb1949 |
| Source note | uspto-grants-2000_10 |