HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → tert-butyl 3(3-pentyl)-L-phenylalaninate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isobutylene | HCID 8255 | — |
| Reactant | 3-(3-pentyl)-L-phenylalanine | HCID 20637683 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | tert-butyl 3(3-pentyl)-L-phenylalaninate | HCID 20637699 | 74% |
Reaction Steps
According to example 54, 0.60 g of 3-(3-pentyl)-L-phenylalanine.HCl was treated with 30 mL of isobutylene in 35 mL of 1,4-dioxane in the presence of 0.5 mL of conc. H2SO4. Work-up in the usual manner followed by acidification with 2 mL of 1N ethereal HCl afforded 0.53 g (74%) of tert-butyl 3-(3-pentyl)-L-phenylalaninate.HCl as a light yellow glass.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06140100 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-a8e8b986f0a6489eacc8a96f01872a6f |
| Source note | uspto-grants-2000_10 |