HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(2-thienyl)heptanoate → (E)-3-[2-n-Butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-{1-(2-thienyl)pentyl}-2-propenoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(2-thienyl)heptanoate | HCID 11775885 | — |
| Reactant | 1-(2-chlorophenyl)methyl-5-carboxymethyl-2-propylthio-1H-imidazole | HCID 19351554 | — |
| Reactant | E-3-[1-(2-chlorophenyl)methyl-2-propylthio-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid | HCID 19936813 | — |
| Reactant | (E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(4-pyridyl)-methyl-2-propenoic acid | HCID 86746549 | — |
| Product | (E)-3-[2-n-Butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-{1-(2-thienyl)pentyl}-2-propenoic Acid | HCID 10027726 | — |
Reaction Steps
The title compound was prepared using the procedure of Example 1 (i, ii, iii, iv [Method B]) replacing methyl 3-(2 -thienyl) propanoate with methyl 3-(2-thienyl)heptanoate; mp 161°-163° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05418250 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-8e0208e405484efaa6035ece4b3ae725 |
| Source note | uspto-grants-1995_05 |