HRID36997

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID566367

Methyl 3-(thiophen-2-yl)propanoate

C8H10O2S

HCID10334966

METHYL 4-[(2-BUTYL-5-FORMYL-1H-IMIDAZOL-1-YL)METHYL]BENZOATE

C17H20N2O3

结构：CCCCc1ncc(C=O)n1Cc1ccc(C(=O)OCC)cc1Cl

HCID19936789

未命名化合物

结构：CCCCc1ncc(/C(C)=C(/C(=O)O)c2ccncc2)n1Cc1ccccc1Cl

HCID86746549

未命名化合物

PRODUCTS

生成物

$结构：CCCCc1ncc(/C=C(\Cc2cccs2)C(=O)O)n1Cc1cccc(C(=O)O)c1$

HCID14952918

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the procedure of Example 1 (iv, Method B) using 2-n-butyl-1-[(4-carbomethoxyphenyl)methyl]imidazole-5-aldehyde (prepared by the method described for the preparation of 2-n-butyl-1-[(4-carboethoxy-2-chlorophenyl)methyl]imidazole-5-aldehyde in Example 42) and methyl 3-(2-thienyl)propanoate; mp 243°-244° C.

WORKUP

后处理

customprepared by the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-afc28e68b9774b42bf1499d87734303a
来源数据集: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05418250
来源说明: uspto-grants-1995_05

反应 SMILES

C(C1N(CC2C=CC=CC=2Cl)C(/C(/C)=C(\C2C=CN=CC=2)/[C:12]([OH:14])=[O:13])=CN=1)CCC.[CH2:30]([C:34]1[N:35]([CH2:41][C:42]2[CH:47]=[CH:46][C:45](C(OC)=O)=[CH:44][CH:43]=2)[C:36]([CH:39]=O)=[CH:37][N:38]=1)[CH2:31][CH2:32][CH3:33].C(C1N(CC2C=CC(C(OCC)=O)=CC=2Cl)C(C=O)=CN=1)CCC.[S:76]1[CH:80]=[CH:79][CH:78]=[C:77]1[CH2:81][CH2:82][C:83]([O:85]C)=[O:84]>>[CH2:30]([C:34]1[N:35]([CH2:41][C:42]2[CH:43]=[CH:44][CH:45]=[C:46]([C:12]([OH:14])=[O:13])[CH:47]=2)[C:36](/[CH:39]=[C:82](\[CH2:81][C:77]2[S:76][CH:80]=[CH:79][CH:78]=2)/[C:83]([OH:85])=[O:84])=[CH:37][N:38]=1)[CH2:31][CH2:32][CH3:33]