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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 370059Generated: October 31, 2026

Ammonia → HCID 23283703, compound

https://huagongshe.com/reaction/370059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHydrochloric AcidHCID 313—
ReactantDimethyl SulfoxideHCID 679—
ReactantHCID 23283702HCID 23283702—
ProductHCID 23283703HCID 23283703—

Reaction Steps

145 mg of N-[2-(5-methoxyindol-3-yl)ethyl]glutarimide are dissolved in DMSO (30 μl) in a round-bottomed flask and concentrated HCl (72 μl) is added with stirring. The mixture is stirred overnight at room temperature. The crude product is neutralized with NH3 and then extracted with EtOAc. After separation on a silica plate, N-[2-(5-methoxy-2-oxo-2,3-dihydroindol-3-yl)ethyl]glutarimide is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06140372
Source datasetuspto-grants-2000_10
ORD IDord-39ccf2a2f91c48b9a9ce7785531a9364
Source noteuspto-grants-2000_10