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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 370314Generated: October 30, 2026

Chloro-N,N-dimethylformiminium chloride → 1-(4-Cyanobenzyl)-5-(chloromethyl)imidazole

https://huagongshe.com/reaction/370314

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloro-N,N-dimethylformiminium chlorideHCID 77311—
Reactant1-(4-Cyanobenzyl)-5-hydroxymethyl-1H-imidazoleHCID 10198247—
Product1-(4-Cyanobenzyl)-5-(chloromethyl)imidazoleHCID 9795358—

Reaction Steps

combining 1-(4-Cyanobenzyl)-5-Hydroxymethyl-imidazole of formula IA ##STR37## with Vilsmeier reagent to obtain 1-(4-Cyanobenzyl)-5-Chloromethylimidazole of formula IF: ##STR38##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06140508
Source datasetuspto-grants-2000_10
ORD IDord-d8d6b7ae11914057ba56a68d654b9cee
Source noteuspto-grants-2000_10