HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2-(3'-Chlorophenyl)-5,5-dimethyl-1,3-cyclohexanedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Ethyl 6-(3'chlorophenyl)-6-cyano-5-keto-3,3-dimethylhexanoate | HCID 20275820 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(3'-Chlorophenyl)-5,5-dimethyl-1,3-cyclohexanedione | HCID 13259772 | 46.4% |
Reaction Steps
Starting with 108.08 g (0.351 mol) of ethyl 6-(3'-chlorophenyl)-6-cyano-5-keto-3,3-dimethylhexanoate, 316 ml of acetic acid, 105 ml of water, and 105 ml of concentrated sulfuric acid, and utilizing the procedure described in Example 1, Part B, 40.82 g (46% yield) of 2-(3'-chlorophenyl)-5,5-dimethyl-1,3-cyclohexanedione was obtained as a white solid, m.p. 155°-58° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04526723 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-887f0ca51454447e8af1df5c181047dd |
| Source note | uspto-grants-1985_07 |