HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 370442Generated: October 30, 2026
Methanol → 3-(4-Pyridyl)-4-methyl-5-methoxy-pyrazole
https://huagongshe.com/reaction/370442
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 3-(4-Pyridyl)-4-methyl-5-pyrazolone | HCID 20276054 | — |
| Reactant | N-ethoxycarbonyliminocarbamate | HCID 86599450 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(4-Pyridyl)-4-methyl-5-methoxy-pyrazole | HCID 178494297 | — |
Reaction Steps
1.5 mg of 3-(4-pyridyl)-4-methyl-5-pyrazolone, 2.3 g of triphenylphosphine and 0.27 g of methanol were placed in 30 ml of tetrahydrofuran. The mixture was cooled on an ice bath to 2° C. and 1.6 g of ethyl azodicarboxylate dissolved in 9 ml of tetrahydrofuran was added dropwise.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04526895 |
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| Source dataset | uspto-grants-1985_07 |
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| ORD ID | ord-70b9a7316e8348f29b11c4f69a806619 |
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| Source note | uspto-grants-1985_07 |
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