Water → HCID 16784615, compound

Participants

Reaction Steps

12.3 g of 2-(2-isopropylphenoxy)-1-methylethylazide was dissolved in 150 ml of ether and added portionwise with small amount of lithium aluminium hydride up to 18 g and stirred at room temperature for 2.5 hr. Then 1.8 ml of water, 1.8 ml oif 15% aqueous solution of sodium hydroxide and 5.4 ml of water were added one after another in order to decompose the residual lithium aluminium hydride. Crystals thus isolated were filtered off and washsed with ether; the ether layer was washed consecutively with water and saturated saline and dried with anhydrous sodium sulfate. The solvent was distilled off under reduced pressure and yielded 9.8 g of 2-(2-isopropylphenoxy)-1-methylethylamine. Physical properties of this substance are as the following:

Provenance & Evidence