Iodoethane → HCID 70478347, compound

Participants

Reaction Steps

5.0 g of methyl 3-acetamido-2,3,6-trideoxy-β-L-lyxohexopyranoside were heated at 45° C. in the dark in a mixture of 25 ml of ethyl iodide and 20 ml of dimethylformamide containing 10 g of silver oxide. After 17 hours, the mixture was filtered through Celite and the filtrate was evaporated. The gum obtained was purified by column chromatography to give 3.4 g of methyl 3-acetamido-2,3,6-trideoxy-4-O-ethyl-β-L-lyxohexopyranoside in the form of colourless crystals of melting point 199°-200° C.; [α]D20 =-75.0° (c=0.5% in methanol).

Provenance & Evidence