Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | HCID 20275282 | HCID 20275282 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178433541 | HCID 178433541 | — |
Reaction Steps
A mixture of 14.5 g (85 mmole) of 5-chloro-7-methyltriazolo[1,5-c]pyrimidine and 15 g (200 mmole) of thiourea in 100 ml of methanol was heated at reflux for one hour, and then cooled to 0° C. The product was collected by filtration and recrystallized from a 50:50 mixture of ethanol and hexanes with treatment with decolorizing charcoal to provide 7-methyltriazolo[1,5-c]pyrimidine-5-thiol. The structural assignment was confirmed by nuclear magnetic resonance spectral analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04528288 |
|---|
| Source dataset | uspto-grants-1985_07 |
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| ORD ID | ord-f412fe5d25d04309ab404403a817fc8c |
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| Source note | uspto-grants-1985_07 |
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