HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-(4-Methyl-1-piperidinyl)-5-nitro-4'-chlorobenzophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Methylpiperidine | HCID 69381 | — |
| Reactant | (2-Chloro-5-nitro-phenyl)-(4-chloro-phenyl)-methanone | HCID 875720 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(4-Methyl-1-piperidinyl)-5-nitro-4'-chlorobenzophenone | HCID 13105502 | 71.7% |
Reaction Steps
A mixture of 0.07 mole (20.7 g) of 2,4'-dichloro-5-nitrobenzophenone, of 0.1 mole (11.4 ml) of 4-methyl-piperidine and of 10 g of K2CO3 in 100 ml of anhydrous ethanol is heated to reflux for 3 hours. After cooling of the reaction medium, the precipitate obtained is filtered, washed with water, dried then recrystallized from ethanol. 18 g (yield=71.7%) of the expected product are thus obtained. M.p.=136° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04528294 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-02d7334024ea4d22a3a2a4fee15e4adf |
| Source note | uspto-grants-1985_07 |