HCID 20275380, compound → HCID 20275379, compound

HRID 370729Notes

Reaction equation

HRID 370729 reaction equation
C([S:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[C:15]([C:16]([O:18][CH3:19])=[O:17])=[CH:14][N:13]=[CH:12][CH:11]=1)=[O:8])(=O)C.C(SCC(C)C(NC1N=CC=CC=1C(OC)=O)=O)(=O)C>>[SH:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[C:15]([C:16]([O:18][CH3:19])=[O:17])=[CH:14][N:13]=[CH:12][CH:11]=1)=[O:8]

Participants

3

Reactant 2

HCID 20275380HCID 20275380, compoundHCID 20275381HCID 20275381, compound

Product 1

HCID 20275379HCID 20275379, compound

Procedure

Following the procedure of Example 2, but substituting an equivalent amount of methyl 4-(2-acetylthiomethyl-propionamido)-nicotinate, obtained as disclosed in Example 4, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate, methyl 4-(2-mercaptomethyl-propionamido)-nicotinate is obtained, m.p. 54°-56° C., from petroleum ether.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-f292410dc8704a719a955edb212d1f48
Source dataset
uspto-grants-1985_07
Patent number
US04528296

Reaction notes

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