HCID 20275380, compound → HCID 20275390, compound

HRID 370730Notes

Reaction equation

HRID 370730 reaction equation
C([S:4][CH2:5][CH:6]([CH3:21])[C:7]([NH:9][C:10]1[CH:20]=[CH:19][C:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:12][N:11]=1)=[O:8])(=O)C.C(SCC(C)C(NC1N=CC=CC=1C(OC)=O)=O)(=O)C>>[SH:4][CH2:5][CH:6]([CH3:21])[C:7]([NH:9][C:10]1[CH:20]=[CH:19][C:13]([C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:12][N:11]=1)=[O:8]

Participants

3

Reactant 2

HCID 20275380HCID 20275380, compoundHCID 20275383HCID 20275383, compound

Product 1

HCID 20275390HCID 20275390, compound

Procedure

Following the procedure of Example 2, but substituting an equivalent amount of ethyl 6-(2-acetylthiomethyl-propionamido)-nicotinate, obtained as disclosed in Example 6, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate, ethyl 6-(2-mercaptomethyl-propionamido)-nicotinate is obtained; m.p. 58°-61° C. from petroleum ether.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-c80c1af841c0418ab012d0aeee371b30
Source dataset
uspto-grants-1985_07
Patent number
US04528296

Reaction notes

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