HCID 20275380, compound → HCID 20275389, compound

HRID 370731Notes

Reaction equation

HRID 370731 reaction equation
C([S:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[N:15]=[C:14]([C:16]([O:18]C)=[O:17])[CH:13]=[CH:12][CH:11]=1)=[O:8])(=O)C.C(SCC(C)C(NC1N=CC=CC=1C(OC)=O)=O)(=O)C>>[SH:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[N:15]=[C:14]([C:16]([OH:18])=[O:17])[CH:13]=[CH:12][CH:11]=1)=[O:8]

Participants

3

Reactant 2

HCID 20275380HCID 20275380, compoundHCID 20275392HCID 20275392, compound

Product 1

HCID 20275389HCID 20275389, compound

Procedure

Following the procedure of Example 3, but substituting an equivalent amount of methyl 6-(2-acetylthiomethyl-propionamido)-picolinate, obtained as disclosed in Example 9, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate, 6-(2-mercaptomethyl-propionamido)-picolinic acid is obtained; m.p. 178°-179° C., from acetone/ethyl acetate.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-08efa26c10914178995c76681e44c235
Source dataset
uspto-grants-1985_07
Patent number
US04528296

Reaction notes

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