HCID 20275380, compound → HCID 20275377, compound

HRID 370736Notes

Reaction equation

HRID 370736 reaction equation
C([S:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]([O:18]C)=[O:17])=[N:14][CH:15]=1)=[O:8])(=O)C.C(SCC(C)C(NC1N=CC=CC=1C(OC)=O)=O)(=O)C>>[SH:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]([OH:18])=[O:17])=[N:14][CH:15]=1)=[O:8]

Participants

3

Reactant 2

HCID 20275380HCID 20275380, compoundHCID 20275385HCID 20275385, compound

Product 1

HCID 20275377HCID 20275377, compound

Procedure

Following the procedure of Example 3, but substituting an equivalent amount of methyl 5-(2-acetylthiomethyl-propionamido)-picolinate, obtained as disclosed in Example 21, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate, 5-(2-mercaptomethyl-propionamido)-picolinic acid is obtained; m.p. 175°-177° C., from acetone.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-61578de9bd9d41a2b68e02c48ff6fa22
Source dataset
uspto-grants-1985_07
Patent number
US04528296

Reaction notes

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