HCID 20275373, compound → HCID 20275391, compound

HRID 370740Notes

Reaction equation

HRID 370740 reaction equation
C([S:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[CH:11]=[C:12]([CH:17]=[CH:18][N:19]=1)[C:13]([O:15]C)=[O:14])=[O:8])(=O)C.C(SCC(C)C(NC1N=CC=CC=1C(OC)=O)=O)(=O)C>>[SH:4][CH2:5][CH:6]([CH3:20])[C:7]([NH:9][C:10]1[CH:11]=[C:12]([CH:17]=[CH:18][N:19]=1)[C:13]([OH:15])=[O:14])=[O:8]

Participants

3

Reactant 2

HCID 20275373HCID 20275373, compoundHCID 20275380HCID 20275380, compound

Product 1

HCID 20275391HCID 20275391, compound

Procedure

Following the procedure of Example 3, but substituting an equivalent amount of methyl 2-(2-acetylthiomethyl-propionamido)-isonicotinate, obtained as disclosed in Example 29, for methyl 2-(2-acetylthiomethyl-propionamido)-nicotinate; 2-(2-mercaptomethyl-propionamido)-isonicotinic acid is obtained; m.p. 247°-248° C., from ethanol/water.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-c53c98590a51464bbaa0d1e1459be090
Source dataset
uspto-grants-1985_07
Patent number
US04528296

Reaction notes

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