HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfur dichloride → 3-Amino-4-[3-(3-piperidinomethylphenoxy)propylamino]-1,2,5-thiadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfur dichloride | HCID 25353 | — |
| Reactant | HCID 178478600 | HCID 178478600 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Amino-4-[3-(3-piperidinomethylphenoxy)propylamino]-1,2,5-thiadiazole | HCID 6917743 | — |
Reaction Steps
To a stirred suspension of N-[3-(3-piperidinomethylphenoxy)propyl]ethanediimidamide trihydrochloride (854 mg; 2 mmoles) in 6 mL of DMF under N2 in an ice bath was added SCl2 (206 mg; 2 mmoles) in 2 mL of DMF. The reaction mixture was stirred at ambient temperature and the title compound was produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04528375 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-a57d84c46f1d4ccb993356fa2b7a0043 |
| Source note | uspto-grants-1985_07 |