Ethanolamine → HCID 19934774, compound

HRID 37097Notes

Reaction equation

HRID 37097 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[C:20]([O:21][C:22]3[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:23]=3[Cl:30])=[C:19]([CH2:31]Cl)[N:18]=[CH:17][N:16]=2)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH2:33]([CH2:35][NH2:36])[OH:34]>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[C:20]([O:21][C:22]3[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:23]=3[Cl:30])=[C:19]([CH2:31][NH:36][CH2:35][CH2:33][OH:34])[N:18]=[CH:17][N:16]=2)(=[O:12])=[O:13])=[CH:7][CH:6]=1)([CH3:3])([CH3:2])[CH3:4]

Participants

3

Reactant 2

HCID 700EthanolamineHCID 199347424-tert-butyl-N-[6-chloromethyl-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulphonamide

Product 1

HCID 19934774HCID 19934774, compound

Procedure

By reacting 4-tert-butyl-N-[6-chloromethyl-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulphonamide with ethanolamine there was obtained 4-tert-butyl-N-[5-(2-chloro-5-methoxy-phenoxy)-6-(2-hydroxy-ethylaminomethyl)-pyrimidin-4yl]-benzenesulphonamide.

Sources & evidence

ORD record
ord-26d7bba25a444fda9c4c5d1935446a9b
Source dataset
uspto-grants-1995_05
Patent number
US05420129

Reaction notes

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