反应详情

To 5.31 g of 2,3-dichloroanisole is slowly added 10 ml of chlorosulfonic acid over a period of 30 minutes. The reaction is mildly exothermic and at the end of the addition, a clear solution is formed. The yellowish solution is stirred at room temperature for 1 additional hour and quenched with 200 g of crushed ice. The solid is filtered, air-dried and recrystallized from ether-pentane to give 6.9 g of 2,3-dichloro-4-methoxybenzenesulfonyl chloride as off-white prisms, mp 93°-95°.

1. customof 30 minutes
2. additionThe reaction is mildly exothermic and at the end of the addition
3. customa clear solution is formed
4. customquenched with 200 g of crushed ice
5. filtrationThe solid is filtered
6. customair-dried
7. customrecrystallized from ether-pentane