HRID37098

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10268

3-Furoic acid

C5H4O3

结构：COc1ccc(Cl)c(Oc2c(COCCO)ncnc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1

HCID19934741

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(Cl)c(Oc2c(COCCOC(=O)c3ccoc3)ncnc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1

HCID69960040

未命名化合物

PROCEDURE

实验过程

By reacting 4-tert-butyl-N-[5-(2-chloro-5-methoxy-phenoxy)-6-(2-hydroxy-ethoxy-methyl)-pyrimidin-4-yl]-benzenesulphonamide with 3-furancarboxylic acid there was obtained furan-3-carboxylic acid 2-[6-(4-tert-butyl-phenylsulfonylamino)-5-(2-chloro-5-methoxy-phenoxy)-pyrimidin-4-ylmethoxy]-ethylester. MS: (M+H)+=618.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-71de7082379e4214bc8b7c7b7bd2b60f
来源数据集: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05420129
来源说明: uspto-grants-1995_05

反应 SMILES

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[C:20]([O:21][C:22]3[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:23]=3[Cl:30])=[C:19]([CH2:31][O:32][CH2:33][CH2:34][OH:35])[N:18]=[CH:17][N:16]=2)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[O:36]1[CH:40]=[CH:39][C:38]([C:41](O)=[O:42])=[CH:37]1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[N:16]=[CH:17][N:18]=[C:19]([CH2:31][O:32][CH2:33][CH2:34][O:35][C:41]([C:38]3[CH:39]=[CH:40][O:36][CH:37]=3)=[O:42])[C:20]=2[O:21][C:22]2[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:23]=2[Cl:30])(=[O:12])=[O:13])=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]