Sodium borohydride → HCID 20252424, compound

HRID 371040Notes

Reaction equation

HRID 371040 reaction equation
[Cl:1][C:2]1[C:3]([O:12][C:13]2[CH:29]=[CH:28][C:16]([O:17][CH:18]([CH3:27])[C:19](=[O:26])[CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:15][CH:14]=2)=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[BH4-].[Na+]>C(O)C>[Cl:1][C:2]1[C:3]([O:12][C:13]2[CH:29]=[CH:28][C:16]([O:17][CH:18]([CH3:27])[CH:19]([OH:26])[CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:15][CH:14]=2)=[N:4][CH:5]=[C:6]([C:8]([F:10])([F:9])[F:11])[CH:7]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 13472761HCID 13472761, compound

Product 1

HCID 20252424HCID 20252424, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl 4-[4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy]-3-oxopentanoate (680 mg) is reduced using NaBH4 (60 mg) in ethanol (10 ml) to yield ethyl 4-[4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy]-3-hydroxypentanoate

Sources & evidence

ORD record
ord-9bb7c797d76746a9afcb93ada1d0a965
Source dataset
uspto-grants-1985_07
Patent number
US04529438

Reaction notes

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