HCID 13992981, compound → HCID 131714261, compound

HRID 371071Notes

Reaction equation

HRID 371071 reaction equation
[CH:1]1([NH:7][C:8](=[O:16])[C@H:9]([CH2:11][CH2:12][C:13](=[O:15])[NH2:14])[NH2:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>CO>[OH2:15].[CH:1]1([NH:7][C:8](=[O:16])[C@H:9]([CH2:11][CH2:12][C:13](=[O:15])[NH2:14])[NH2:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[NH2:10][C@H:9]([C:8]([NH:7][CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)=[O:16])[CH2:11][CH2:12][C:13](=[O:15])[NH2:14]

Participants

3

Reactant 1

HCID 13992981HCID 13992981, compound

Product 1

HCID 131714261HCID 131714261, compoundYield 214.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

1.52 g of sulfodehydroabietic acid monohydrate is dissolved in 5 ml of methanol, and a solution of 0.907 g of L-glutamine cyclohexylamide in 20 ml of methanol is added thereto. The mixture is concentrated under reduced pressure to remove solvent until the volume of said mixture is 5 ml. Ether is added to the residue and the precipitates (white crystalline) are collected therefrom. 1.35 g of sulfodehydroabietic acid L-glutamine cyclohexylamide salt hemihydrate is thereby obtained.

Workup

  1. concentrationThe mixture is concentrated under reduced pressure
  2. customto remove solvent until the volume of said mixture
  3. additionEther is added to the residue
  4. customthe precipitates (white crystalline)
  5. customare collected

Sources & evidence

ORD record
ord-d472dd8ac06c4fb3ad21e389d88605c1
Source dataset
uspto-grants-1985_07
Patent number
US04529602

Reaction notes

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