反应详情

To a solution of 0.474 g of 2-(6-amino-3,4-dihydro-2,2-dimethyl-2H-1,4-benzoxazin-4-yl)pyridine N-oxide in 5 ml of acetic anhydride was added 3 drops of pyridine and the mixture was stirred at room temperature for 63 hours. After concentration, the residue was dissolved in chloroform, washed with saturated aqueous sodium hydrogen carbonate solution, dried and concentrated. The residue was recrystallized from chloroform-ether to give 0.285 g of 2-(6-acetamido-3,4-dihydro-2,2-dimethyl-2H-1,4-benzoxazin-4-yl)pyridine N-oxide.

1. concentrationAfter concentration
2. dissolutionthe residue was dissolved in chloroform
3. washwashed with saturated aqueous sodium hydrogen carbonate solution
4. customdried
5. concentrationconcentrated
6. customThe residue was recrystallized from chloroform-ether