HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 12769709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1(3H)-Isobenzofuranone, 3-bromo- | HCID 96218 | — |
| Reactant | 4-([1,1'-Biphenyl]-4-yl)-3-hydroxybutanoic acid | HCID 192832 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 12769709 | HCID 12769709 | 71% |
Reaction Steps
To a solution of 7.7 g of 3-hydroxy-4-(4-biphenylyl)butyric acid in 40 ml of chloroform and 3.4 g of triethylamine is added a solution of 6.2 g of 3-bromophtalide in 20 ml of chloroform. The solution thus obtained is stirred for 24 hours at room temperature, the organic phase is washed with an aqueous solution of sodium bicarbonate, then with water and finally it is dried on anhydrous sodium sulfate and evaporated to yield the phthalidyl 3-hydroxy-4-(4-biphenylyl)butyrate; yield 71%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04529737 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-f6cb25683a7a464d9918247296a6a7e0 |
| Source note | uspto-grants-1985_07 |