Thionyl Chloride → HCID 57100648, compound

Participants

Reaction Steps

Thionyl chloride (25 ml) is dropwise added to the ester (3) (47.6 g). After 30 minutes at 30° C., the mixture is distilled in vacuo (b.p. 104°-105° C./7 mmHg, Yield: 43 g). To the distillate are added benzene (82 ml) and DBU (42 ml), and the mixture is heated under reflux for 1.5 hours. The reaction mixture is washed with water and distilled in vacuo to give methyl vinylthioacetate (4). Yield: 24.7 g, b.p. 59°-65.5° C.4-5 mmHg.

Provenance & Evidence