HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 178513892, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 53779291 | HCID 53779291 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178513892 | HCID 178513892 | — |
Reaction Steps
A mixture of methyl 2-(2-chlorovinyl)thio-2-carboxyacetate (1) (450 mg), oxalyl chloride (325 mg) and dimethylformamide (50 mg) is stirred in dichloromethane (2 ml) at room temperature for 30 minutes. To the mixture is added a solution of sodium azide (550 mg) dissolved in acetone (2 ml) and water (2 ml). The mixture is stirred for 30 minutes, diluted with dichloromethane, washed with water, and cencentrated in vacuo to give azide (2). Yield: 430 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04529721 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-3cb2cd8b8de84b97ae26100577fca965 |
| Source note | uspto-grants-1985_07 |