HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → Methyl 2-(1-t-butoxycarbonyl-1-phenylthiomethylene)-1,3-dithietane-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Benzenesulfenyl chloride | HCID 11008040 | — |
| Reactant | Methyl 2-(t-butoxycarbonylmethylene)-1,3-dithietane-4-carboxylate | HCID 20274244 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 2-(1-t-butoxycarbonyl-1-phenylthiomethylene)-1,3-dithietane-4-carboxylate | HCID 20274259 | — |
Reaction Steps
A mixture of methyl 2-(t-butoxycarbonylmethylene)-1,3-dithietane-4-carboxylate (689 mg), pyridine (430 μl) and benzenesulfenyl chloride is allowed to react in methylene chloride at 0° C. until no starting carboxylate is detected. The reaction mixture is washed with water, dried, and vacuum evaporated to give methyl 2-(1-t-butoxycarbonyl-1-phenylthiomethylene)-1,3-dithietane-4-carboxylate. Yield: 713 mg (73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04529721 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-65ee250340974e8aa798484f2e9d38eb |
| Source note | uspto-grants-1985_07 |