4-Nitroaniline → 1-Methyl-3-(4-nitrophenyl)-1H-pyrrole-2,5-dione

HRID 371132Notes

Reaction equation

[CH3:1][N:2]1[C:6](=[O:7])[CH:5]=[CH:4][C:3]1=[O:8].[N+:9]([C:12]1[CH:18]=[CH:17][C:15](N)=[CH:14][CH:13]=1)([O-:11])=[O:10]>>[N+:9]([C:12]1[CH:18]=[CH:17][C:15]([C:4]2[C:3]([N:2]([CH3:1])[C:6](=[O:7])[CH:5]=2)=[O:8])=[CH:14][CH:13]=1)([O-:11])=[O:10]

Participants

Reactant 2

HCID 74754-Nitroaniline

HCID 70261N-Methylmaleimide

Product 1

HCID 135195741-Methyl-3-(4-nitrophenyl)-1H-pyrrole-2,5-dione

Procedure

A 100 g portion of N-methylmaleimide was reacted with 126.2 g of p-nitroaniline as described in Example 6, giving 78 g of 2-(p-nitrophenyl)-N-methylmaleimide.

Sources & evidence

ORD record: ord-a59dc0d94248434f9ba5b9c289d10fa7
Source dataset: uspto-grants-1985_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04529736

Reaction notes

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