HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → Cyclopentanecarboxylic acid, 2-oxo-1-(3-oxobutyl)-, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Methyl vinyl ketone | HCID 6570 | — |
| Reactant | Ethyl 2-oxocyclopentanecarboxylate | HCID 69136 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Cyclopentanecarboxylic acid, 2-oxo-1-(3-oxobutyl)-, ethyl ester | HCID 11806371 | — |
Reaction Steps
A mixture of 102.0 g of ethyl 2-oxocyclopentanecarboxylate, 300 ml of benzene, 67 ml of methyl vinyl ketone and 20 ml of triethylamine was allowed to stir magnetically at reflux for 2.5 hours. Concentration followed by Claisen distillation gave 128 g of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04529806 |
| Source dataset | uspto-grants-1985_07 |
| ORD ID | ord-77703c370b164b45b7970abd384ad3c4 |
| Source note | uspto-grants-1985_07 |