Testosterone → HCID 70488595, compound

Participants

Reaction Steps

To a solution containing 14.7 g of testosterone in 140 ml of toluene, 65 ml methylene chloride, 25 ml of ether and 2.0 ml of water is added 13.65 g of lithium iodide and the resulting mixture is stirred for 2 hours. To aid in filtration of the mixture 160 ml toluene and 50 ml ether is added. The solids are removed by filtration and washed with 2×50 ml of cold wash solution (4:1, hexane:methylene chloride) followed by 100 ml of hexane. The solids are dried `in vacuo` for 16 hours, then under high vacuum for 24 hours to yield 31.73 g of testosterone lithium iodide complex.

Provenance & Evidence