Phosphoric Acid → HCID 178516351, compound

HRID 37133Notes

Reaction equation

C(OC([C:6]1[C:7]([OH:28])=[N:8][C:9]2[N:10]([N:12]=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([S:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:17][CH:16]=2)[CH:11]=1)=O)C.P(=O)(O)(O)O>>[OH:28][C:7]1[CH:6]=[CH:11][N:10]2[N:12]=[CH:13][C:14]([C:15]3[CH:16]=[CH:17][C:18]([S:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[CH:19][CH:20]=3)=[C:9]2[N:8]=1

Participants

Reactant 2

HCID 1004Phosphoric Acid

HCID 178469449HCID 178469449, compound

Product 1

HCID 178516351HCID 178516351, compoundYield 50.3%

Procedure

In the same manner as in Example 3 except that 0.39 g of 6-ethoxycarbonyl-5-hydroxy-3-(4-phenylthiophenyl)-pyrazolo[1,5-a]pyrimidine obtained in Example 2 and 5 ml of 85% phosphoric acid were used, 0.16 g of the title compound was obtained.

Sources & evidence

ORD record: ord-729bbd689b9a44578baa54d07dd70937
Source dataset: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05420128

Reaction notes

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