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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 371389Generated: October 26, 2026

Benzyl Bromide → HCID 178439471, compound

https://huagongshe.com/reaction/371389

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178439476HCID 178439476—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178439471HCID 178439471—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 51.1 g (0.3 mole) of 4-hydroxy-6-n-propylpyrimidine-2-thiol, 51.3 g (0.3 mole) of benzyl bromide, 100 ml of dioxane and 500 ml of 1N aqueous sodium hydroxide solution was heated at 80° C. for four hours. After cooling, the solid was collected by filtration to provide white crystals of 2-benzylthio-4-hydroxy-6-n-propylpyrimidine, m.p. 122°-126° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04532242
Source datasetuspto-grants-1985_07
ORD IDord-6326fea142664eb9a26e435da597621f
Source noteuspto-grants-1985_07