反应详情

23.6 g (0.1 mol) of 2-nitro-1-(3nitrophenyl)-but-1-ene-3-one and 10.2 g (0.1 mol) of 2-amino-1-nitro-prop-1-ene in 150 ml of ethanol were heated under reflux for 12 hours. After the mixture had cooled, the solvent was distilled off in vacuo, and the oily residue was taken up in chloroform, and was chromatographed on a silica gel column, using chloroform with the addition of methanol. The product formed yellow crystals of melting point 237°-240° C. (decomposition) in isopropanol.

1. temperatureunder reflux for 12 hours
2. temperatureAfter the mixture had cooled
3. distillationthe solvent was distilled off in vacuo
4. customwas chromatographed on a silica gel column
5. additionwith the addition of methanol
6. customThe product formed yellow crystals of melting point 237°-240° C. (decomposition) in isopropanol