反应详情

8 g (0.03 mol) of diethyl 2-amino-4,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate in 100 ml of acetic anhydride were boiled under reflux for 4 hours. The mixture was concentrated to dryness in vacuo, and the residue was recrystallized from ethanol. Yield: 5.4 g (58% of theory) of m.p.: 105° C.

1. temperatureunder reflux for 4 hours
2. concentrationThe mixture was concentrated to dryness in vacuo
3. customthe residue was recrystallized from ethanol