Dimethyl Sulfate → Methyl 3-methoxy-4-phenylthiobenzoate

Participants

Reaction Steps

To a mixture of 49.11 g of methyl 3-hydroxy-4-phenylthiobenzoate, 27.33 g of potassium carbonate and 627 ml of acetone, 17.85 ml of dimethyl sulfate was added, and the mixture was refluxed for 6 hours while stirring. The reaction mixture was cooled, and the precipitate was filtered and washed with acetone. The filtrate and washing liquid were combined, and concentrated in vacuo, and methyl 3-methoxy-4-phenylthiobenzoate was obtained.

Provenance & Evidence