Potassium Carbonate → HCID 13478347, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.2 g (0.010 mole) of 6-ethyl-5-(1-piperazinyl)-2,4-pyrimidinediamine, 1.33 g (0.011 mole) of a 4-fluorobenzonitrile and 1.52 g (0.011 mole) of potassium carbonate in 20 ml of dimethyl sulfoxide was heated under reflux at 140° C. for two hours. The reaction mixture was cooled and poured into 100 ml of ice water. The solid was collected and recrystallized from N,N dimethyl formamide to give 2.21 g of the product as a white solid, mp>310° C.

Provenance & Evidence