Sodium Carbonate → HCID 13478349, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 9.6 g (0.0407 mole) of 5-(1-piperazinyl)-6-propyl-2,4-pyrimidinediamine, 5.4 g (0.0448 mole) of 4-fluorobenzonitrile and 6.18 g (0.0448 mole) of sodium carbonate in 200 ml of dimethyl sulfoxide was heated at 140° C. for two hours. The reaction mixture was cooled and poured into 500 ml of ice water. The solid was collected and recrystallized from N,N-dimethylformamide to give 11.7 g of the product as a white solid; mp>300° C.

Provenance & Evidence