反应详情

A mixture was 85 g of 3-methyl-4-phenylthiobenzoic acid, 20 ml of concentrated sulfuric acid, and 1.2 liters of methanol was refluxed for 4 hours while stirring. After reaction, the reaction mixture was concentrated in vacuo, and 1.5 liters of ethyl acetate was added to the residue, and the mixture was washed with saturated brine (400 ml×3), and dried with anhydrous sodium sulfate, concentrated in vacuo, and methyl 3-methyl-4-phenylthiobenzoate was obtained (80.33 g).

1. temperaturewas refluxed for 4 hours
2. customAfter reaction
3. concentrationthe reaction mixture was concentrated in vacuo, and 1.5 liters of ethyl acetate
4. additionwas added to the residue
5. washthe mixture was washed with saturated brine (400 ml×3)
6. dry with materialdried with anhydrous sodium sulfate
7. concentrationconcentrated in vacuo