反应详情

温度

150 °C

500 g of the so-obtained 6-bromo-2-methylphenol, together with 10 g zinc shavings, are heated to about 100° C. Within 20 minutes 453 g benzyl chloride are added dropwise with stirring and under moisture exclusion. For a further 12 minutes the reaction mixture is heated to 150° C. It is then held a total of 5 hours at the temperature of 150° C. After cooling, the zinc is separated. The reaction product is distilled in a vacuum at 0.03 up to 0.04 Torr. 305 g 6-bromo-2-methyl-4-benzylphenol are obtained as a weakly yellowish, oily liquid, which is nearly odorless.

1. customa total of 5 hours
2. customat the temperature of 150° C
3. temperatureAfter cooling
4. customthe zinc is separated
5. distillationThe reaction product is distilled in a vacuum at 0.03 up to 0.04 Torr