反应详情

温度

60 °C

117.5 g (0.75 mol) 4-chloro-2-ethylphenol are dissolved with 42.25 g (0.25 mol) 4-isopropylbenzylchloride in 200 ml chloroform. 22.5 g water-free zinc chloride are added thereto for the alkylation reaction. Already at 30° C. a powerful reaction takes place. The entire mixture is after-stirred 5-6 h at 60° C. for completion of the alkylation. After a cooling it is subsequently washed three times each with 200 ml water, and then dried across sodium sulfate, after which the solvent chloroform is driven off.

1. customfor the alkylation reaction
2. customAlready at 30° C. a powerful reaction
3. washAfter a cooling it is subsequently washed three times each with 200 ml water
4. dry with materialdried across sodium sulfate