Tetrahydrofuran → 1-Dipropylcarbamoyl-3-n-butylsulphonyl-1,2,4-triazole

Participants

Reaction Steps

A mixture of 5.7 g. 3-n-butylsulphonyl-1,2,4-triazole, 5.4 g. dipropylcarbamoyl chloride, 25 ml. dry tetrahydrofuran and 6 ml. dry triethylamine was refluxed under anhydrous conditions for 1.5 hours. The reaction mixture was worked up as described in Example 1 to produce a solid product which was recrystallized from petroleum ether (60° - 80° C.) to give 1-dipropylcarbamoyl-3-n-butylsulphonyl-1,2,4-triazole, m.p. 46° - 47° C. Elemental analysis satisfactory.

Provenance & Evidence